Ofc Cover Scan to Fit into This Box
نویسندگان
چکیده
In vivo, copper(II) is a major source of reactive oxygen species (ROS) via Fenton Haber Weiss reactions. Interest in Alzheimer’s disease has led to intensive studies into the generation of ROS catalyzed by copper(II) with or without the presence of β-amyloid (Aβ) peptides and biological antioxidants. We establish a potential connection between tyrosine nitration and copper(II) toxicity in neurodegenerative diseases by demonstrating that tyrosine nitration can be induced by ascorbic acid, nitrite and copper(II) or peptide coordinated copper(II) under aerobic conditions via an in vitro protocol. As featured in:
منابع مشابه
Ofc Cover Scan to Fit into This Box
Organic selenium compounds in plants and yeasts are eff ective chemoprotectants in mammalian cancer. We identifi ed selenomethionine pathways by measuring endogenous and exogenous 82 Se levels and quantifi ed selenium compounds and selenoproteins in mice liver, kidneys, plasma and urine. a The organic Se compounds (particularly selenomethionine [SeMet]) in plants and yeasts are very effective c...
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